8:30 am Coffee reception (Edgewater Ballroom)

HHFI Overview

9:00 am Welcome & Introductions by David Edwards/Justin Hanes

9:10 am Justin Hanes. HHFI – What it is

9:20 am David Edwards. HHFI – How it Succeeds

HHFI Year 1 Projects — Detecting & Preventing Emerging Disease Threats

9:30 am Jim Collins, Resistant anti-virals and anti-fungals — why and how with HHFI

9:45 am Sangeeta Bhatia. Detection and Interception of Pulmonary Disease Using Inhalable Sensors — why and how with HHFI

10:00 am Melanie Ott & Jennifer Doudna. Predicting the next pandemic — why and how with HHFI

10:15 am Q&A with Drs. Bhatia, Collins, Doudna, and Ott. Moderated by Dr. Laurencin.

10:30 am Break

HHFI Year 1 Projects — Vaccinating & Eradicating Infectious Diseases

10:50 am Ana Jaklenec/Bob Langer. A vaccine against HIV by pulsed release injectables — why and how with HHFI

11:05 am Molly Stevens. Room-temperature-stable mucosal vaccines — why and how with HHFI

11:20 am Gene de Juan. Effective therapy to prevent hearing loss — why and how with HHFI

11:35 am Justin Hanes. Non-invasive gene therapy for the human brain — why and how with HHFI

11:50 am Q&A with Drs. Langer, Jaklenec, Stevens, de Juan, and Hanes. Moderated by Dr. Arnold.

12:05 pm Lunch with panel discussion (Edgewater Salon C). Can healthcare translation happen better than it does? Panelists: de Juan, Collins, Bhatia. Moderated by Dr. DeSimone & Dr. Denny Ausiello.

HHFI Year 1 Projects — Regenerating the Human Body

1:00 pm Cato Laurencin. A regenerated human leg — why and how with HHFI

1:15 pm Joe DeSimone. Microprinting tissue vasculature — why and how with HHFI

1:30 pm Q&A with Drs. Laurencin, DeSimone. Moderated by Dr. Langer.

HHFI Year 1 Projects — Sustaining Human Health on the Planet

1:45 pm David Edwards. Global-warming-resistant asthma treatment — why and how with HHFI

2:00 pm Frances Arnold. New enzymes for human and planetary health — why and how with HHFI

2:15 pm Q&A with Drs. Edwards and Arnold. Moderated by Dr. Ott.

2:30 pm Break

3:00 pm Panel discussion: HHFI need — Investor & strategic perspective Panelists: Bob Jackson (Braidwell), Paul Conley (General Inception), Vinita Gupta (Lupin), Ling Wong (Highbury), Matt Tirrell (U. Chicago) Moderated by David Edwards & Justin Hanes

4:00 pm Round table discussion: Making HHFI Happen in 2025

5-6:30 pm Beach cocktail