The Next Breath Global Hydration Study (NBGHS) aims to explore the efficacy and feasibility of airway hydration to save billions of life-years on the planet by lowering risks of respiratory disease — the principal cause of death in low-income countries (1).
As a response to the global health crisis of dirty air, coupled with climate change, the burning of fossil fuels and airborne infectious diseases (2) — the NGBHS builds off decades of scientific research confirming the harm to respiratory health of dry airways (3), the benefits of the sustained breathing relatively humid air (4), and the potential of a low-cost, easily-administered, safe, non-drug hygiene ritual among school age children providing sustained airway hydration for better natural immune defense against poor air quality (5-8).
Twenty eight years ago the Harvard Six City Study determined that an increase of fine particulate matter (PM 2.5) from 10 to 30 μg/m3 reduced human longevity by approximately 3 years (9). By contrast, fine particulate levels in major cities of low-income countries today are often in excess of 300 μg/m3.
The poorest of the world face the possibility of catastrophic loss of life in the near term.
The NGBHS aims to evaluate: 1) the prophylactic efficacy of daily airway hydration to reduce symptoms of chronic and acute respiratory disease among those chronically exposed to dirty air; 2) the practical distribution of and compliance to daily airway hydration among children and their families in low-income regions of the world; and 3) the prophylactic efficacy of daily airway hydration to reduce symptoms of acute and chronic respiratory disease, to limit morbidity, and to prolong lifespan among human populations most at risk in low- and middle-income countries.
The NGBHS initially focuses on supporting research to evaluate the ability to reduce disease symptoms (including cough, inflammation, respiratory performance) among COPD sufferers through daily airway hydration (Phase I). With favorable outcomes, the NGBHS aims to evaluate the practical deployment, adoption, surveillance and population-level health benefit of daily airway hydration in large-scale studies in India (Phase II) and Africa/South America (Phase III) beginning in late 2022.
The Charitable Cause of the NGBHS is to promote adoption to and compliance of daily airway hydration among children in low and middle income countries with an aim to improve human life quality, productivity and lifespan prior to the cleaning of the planet’s atmosphere.
Led by a partnership between Next Breath and the makers of FEND, pioneers in upper airway hydration, all members of the NGBHS consortium adhere to the Charitable Cause, and to commit time, expertise, study materials, and other resources to the humanitarian effort at cost.